Luhan Pharmachem Co., Ltd.

The mitomycins are a family of aziridine-containing natural products isolated from Streptomyces caespitosus orStreptomyces lavendulae. One of these compounds, mitomycin C, finds use as a chemotherapeutic agent by virtue of its antitumour antibiotic activity. It is given intravenously to treat upper gastro-intestinal (e.g.esophageal carcinoma), anal cancers, and breast cancers, as well as by bladder instillation for superficialbladder tumours. It causes delayed bone marrow toxicity and therefore it is usually administered at 6-weekly intervals. Prolonged use may result in permanent bone-marrow damage. It may also cause lung fibrosis and renal damage.

cas no.:50-07-7