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VORICONAZOLE

What is Voriconazole?

Voriconazole is used to treat different kinds of serious fungal infections. It may also be used to treat patients with serious fungal infections who cannot tolerate other types of treatment or do not respond to other types of treatment.

What is Voriconazole used for?

Voriconazole is an antifungal medication. Voriconazole is used to treat infections caused by yeast or other types of fungus. Voriconazole may also be used for purposes other than those listed in this medication guide.

Precautions Before Using Voriconazole

For voriconazole, the following should be considered:

Allergies-Tell your doctor if you have ever had any unusual or allergic reaction to voriconazole or other azole antifungal (e.g., fluconazole [Diflucan], itraconazole [Sporanox], ketoconazole [Nizoral]). Also tell your doctor and pharmacist if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy-Voriconazole has been shown to cause fetal harm. Women should use effective contraception during treatment with voriconazole. However, this medicine may be needed in serious diseases or other situations that threaten the mother’s life. Before taking this medicine, be sure your doctor knows if you are pregnant or plan to become pregnant.

Breast-feeding-It is not known whether voriconazole passes into breast milk. Voriconazole should not be used by nursing mothers unless the benefit outweighs the risk.

Children-Studies on this medicine have been done only in patients 12 and older, and there is no specific information comparing the use of voriconazole in children with use in other age groups.

Older adults-Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. Voriconazole is not expected to cause different side effects or problems in older people than it does in younger adults.

Voriconazole side effects

Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

  • Rash
  • Abdominal or stomach pain; bloating or swelling of face, arms, hands, lower legs, or feet; blurred vision; chills; clay-colored stools; confusion; convulsions; dark urine; decreased urine; dizziness; dry mouth; faintness or light-headedness when getting up from a lying or sitting position;
  • Abnormal kidney function; black, bloody, or tarry stools; bleeding gums; blood in eye; blood in urine or stools; chest pain; eye pain; painful or difficult urination;
  • Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome.
  • Changes in vision; seeing things that are not there
  • Diarrhea; difficulty seeing at night ; disturbance in vision; dry mouth; feeling unusually cold; increased sensitivity of eyes to sunlight; shivering; vomiting
What should you do if you miss a dose?

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a voriconazole overdose may include vision problems, excessive salivation, enlarged pupils, weakness, loss of balance, shortness of breath, or seizure (convulsions).

Storage
  • Keep out of the reach of children.
  • Keep the medicine from freezing. Do not refrigerate.
  • Throw away any unused oral suspension after the date listed on the label.
  • Do not keep outdated medicine or medicine longer than needed. Ask your health care professional how you should dispose of any medicine you do not use. Be sure that any discarded medicine is out of the reach of children.
Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.

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