Luhan Pharmachem Co., Ltd.

Luhan pharmachem Co., Ltd. supplies Paroxetine HCl bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Paroxetine HCl is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.

What is Paroxetine HCl?

Paroxetine hydrochloride is an orally administered psychotropic drug. It is the hydrochloride salt of a phenylpiperidine compound identified chemically as (-)-trans-4R-(4′-fluorophenyl)-3S-[(3′, ‘-methylenedioxyphenoxy) methyl] piperidine hydrochloride hemihydrate and has the empirical formula of C19H20FNO3•HCl•1/2H2O.. The molecular weight is 374.8 (329.4 as free base).

What is the mechanism of action?

Paroexetine hydrochloride is a selective serotonin reuptake inhibitor with a chemical structure unrelated to that of other such drugs. The effectiveness of Paxil CR in the treatment of depression and panic disorder seems to be linked to potentiation of serotonergic activity in the central nervous system resulting from the inhibition of neuronal uptake of serotonin.

How to dose Paroxetine HCl?

In general, the recommended starting paroxetine dose is paroxetine 20 mg once daily (usually in the morning). However, the starting dose for treating panic disorder and for elderly people or people with liver or kidney problems is lower: paroxetine 10 mg once daily. Your healthcare provider may choose to increase the paroxetine dosage if symptoms continue, or decrease the dose if side effects occur.

The maximum paroxetine dose is 50 mg (for depression, generalized anxiety disorder, or post-traumatic stress disorder) or 60 mg (for social anxiety disorder, panic disorder, or obsessive-compulsive disorder).

What are the side effects?

• Abnormal ejaculation
• Abnormal vision
• Constipation
• Somnolence
• Decreased libido
• Sweating
• Female genital disorders

Storage

Store between 59 and 86 degrees F.

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.