Luhan Pharmachem Co., Ltd.

Luhan pharmachem Co., Ltd. supplies Celecoxib bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Celecoxib is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.

What is Celecoxib?

Celecoxib INN is a sulfa non-steroidal anti-inflammatory drug (NSAID) and selective COX-2 inhibitor used in the treatment of osteoarthritis, pills rheumatoid arthritis, buy acute pain, help painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. It is marketed by Pfizer. It is known under the brand name Celebrex or Celebra for arthritis and Onsenal for polyps. Celecoxib is available by prescription in capsule form.

Why is this medication prescribed?

Celecoxib is used to relieve pain, tenderness, swelling and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), and ankylosing spondylitis (arthritis that mainly affects the spine). Celecoxib is also used to treat painful menstrual periods and pain from other causes. It is also used with surgery and other treatments to reduce the number of polyps (abnormal growths) in the colon (large intestine) and rectum in patients with familial adenomatous polyposis (a condition in which hundreds or thousands of polyps form in the colon and cancer may develop). Celecoxib is in a class of NSAIDs called COX-2 inhibitors. It works by stopping the body’s production of a substance that causes pain and inflammation.

How should this medicine be used?

Celecoxib comes as a capsule to take by mouth. It is usually taken once or twice a day. If you are taking up to 200 mg of celecoxib at a time, you may take the medication with or without food. If you are taking more than 200 mg of celecoxib at a time, you should take the medication with food. Ask your doctor or pharmacist if you are not sure if you need to take your medication with food. To help you remember to take celecoxib, take it around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take celecoxib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

What special precautions should I follow?

Before taking celecoxib,

tell your doctor and pharmacist if you are allergic to celecoxib, aspirin or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), sulfa medications, any other medications, or any of the inactive ingredients in celecoxib capsules. Ask your pharmacist for a list of the inactive ingredients.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: amiodarone (Cordarone, Pacerone);angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik); certain antidepressants (mood elevators); atazanavir (Reyataz);clopidogrel (Plavix);codeine (in some cough medications and some pain medications); dextromethorphan (in some cough medications); diuretics (‘water pills’); efavirenz (Sustiva); fluconazole (Diflucan); fluvastatin (Lescol); lithium (Eskalith, Lithobid); certain medications for mental illness; metoprolol (Lopressor, Toprol XL); metronidazole (Flagyl); mexiletine (Mexitil); ondansetron (Zofran); propafenone (Rhythmol); ritonavir (Norvir, in Kaletra); sulfamethoxazole (Bactrim, Septra); sulfinpyrazone (Anturane);tamoxifen (Nolvadex) timolol (Blocadren, Timolide, in some eye drops); tramadol (Ultram); and zafirlukast (Accolate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

tell your doctor if you have or have ever had any of the conditions mentioned in the IMPORTANT WARNING section or asthma, especially if you also have frequent stuffed or runny nose or nasal polyps (swelling of the lining of the nose); swelling of the hands, arms, feet, ankles, or lower legs; or liver or kidney disease.

tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, you plan to become pregnant, or you are breast-feeding. If you become pregnant while taking celecoxib, call your doctor.

if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking celecoxib.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What are the side effects of Celecoxib?

Celecoxib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• diarrhea
• gas or bloating
• sore throat
• cold symptoms

Some side effects can be serious. If you experience any of the following symptoms or those mentioned in the IMPORTANT WARNING section, call your doctor immediately. Do not take any more celecoxib until you speak to your doctor.

• unexplained weight gain
• upset stomach
• excessive tiredness
• unusual bleeding or bruising
• itching
• lack of energy
• loss of appetite
• yellowing of the skin or eyes
• flu-like symptoms
• blisters
• fever
• rash
• hives
• hoarseness
• difficulty swallowing or breathing
• pale skin
• fast heartbeat
• cloudy, discolored, or bloody urine
• back pain
• difficult or painful urination
• frequent urination, especially at night

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.