Luhan Pharmachem Co., Ltd.

Luhan pharmachem Co., Ltd. supplies Atazanavir bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Atazanavir is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.

What is Atazanavir?

Atazanavir (formerly known as BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class. Like other anti-retrovirals, it is used to treat infection of human immunodeficiency virus (HIV).

Atazanavir is distinguished from other PIs in that it can be given once-daily (rather than requiring multiple doses per day) and has lesser effects on the patient’s lipid profile (the amounts of cholesterol and other fatty substances in the blood). Like other protease inhibitors, it is used only in combination with other HIV medications. The U.S. Food and Drug Administration (FDA) approved Atazanavir on June 20, 2003.

What is the mechanism of action?

Atazanavir inhibits the virus-specific processing of viral Gag and Gag-Pol poliproteins of HIV-1 group M subtype A, B, C, D, AE, AG, F, G, and J in infected cells, thus preventing formation of mature virions.

How to dose Atazanavir?

Atazanavir comes in the following four strengths:

• 100-mg capsules (brand name: Reyataz).
• 150-mg capsules (brand name: Reyataz).
• 200-mg capsules (brand name: Reyataz).
• 300-mg capsules (brand name: Reyataz).

Take Atazanavir according to your health care provider¡¯s instructions. Take Atazanavir with food.

What are the side effects?

Nausea, vomiting and diarrhoea. Taste disturbances, abdominal pain, anorexia, increased appetite, flatulence, asthenia, fatigue, sleep disturbances, headache, dizziness, paraesthesia, hypoaesthesia, myalgia, arthralgia, alopecia, pruritus and renal insufficiency. Myositis and rhabdomyolysis. Skin rashes may occasionally be severe.

Storage

Store Atazanavir at room temperature, 59 degrees F to 86 degrees F (15 degrees C to 30 degrees C). Do not store Atazanavir in a damp place, such as a bathroom medicine cabinet or near the kitchen sink. Keep Atazanavir in a tightly closed container.

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.