Luhan Pharmachem Co., Ltd.

Luhan pharmachem Co., Ltd. supplies Ansamitocin bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Ansamitocin is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.

We supply from small R&D to commercial Quantity.

What is Ansamitocin?

Ansamitocin P-3 is a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29. It shares the same binding site as rhizoxin and phomopsin A on porcine brain tubulin. Maytansine and its analogs cause extensive disassembly of the microtubule and totally prevent tubulin spiralization. Ansamitocin P-3 is a fungal metabolite with antimitotic, antimitotic activity. Ansamitocin P-3 binds to tubulin and inhibits vinblastine-induced spiral formation.

More  information

CAS No.:66584-72-3

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