Luhan Pharmachem Co., Ltd.

Luhan pharmachem Co., Ltd. supplies Epoprostenol bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Epoprostenol is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.

What is Epoprostenol?

Epoprostenol (PGI2, mind PGX, prostacyclin), a metabolite of arachidonic acid, is a naturally occurring prostaglandin with potent vasodilatory activity and inhibitory activity of platelet aggregation.

Epoprostenol is (5Z,9?,11?,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid.

Epoprostenol sodium has a molecular weight of 374.45 and a molecular formula of C20H31NaO5.

Epoprostenol sodium is indicated for the treatment of pulmonary arterial hypertension (WHO Group 1) to improve exercise capacity. Studies establishing effectiveness included predominantly patients with NYHA Functional Class III-IV symptoms and etiologies of idiopathic or heritable PAH or PAH associated with connective tissue diseases.

Side effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal skin sensations (eg, burning, numbness, tingling); agitation; anxiety; back pain; diarrhea; dizziness; flu-like symptoms (eg, mild fever, mild chills, muscle aches); flushing; headache; loss of appetite; mild pain or redness at the injection site; muscle, bone, joint, or jaw pain; nausea; nervousness; stomach pain; sweating; tiredness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or dark urine; chest pain; dark, tarry, or bloody stools; fainting; fast, slow, or irregular heartbeat; light-headedness; new or worsening shortness of breath; pale skin; severe or persistent dizziness; skin ulcers; swelling of the hands, arms, ankles, or feet; swelling of the stomach; symptoms of infection (eg, fever, chills, persistent sore throat, cough); tremor; unusual or increased bruising or bleeding; unusual tiredness or weakness.

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.